Most Emotional Movie or TV Scene

[Admiral Yi]

Prompted by the Futurama discussion.

No way to do this without spoilers.

I vote for the scene in Sophie's Choice when she has to choose between her son and her daughter.

[Barrister]

Opening scenes from Up.

[mongers]

The End of 'Slient Running'

[PDH]

Final charge in "Glory"

[celedhring]

Opening scenes from Up.

When Miguel sings with his mom in Coco.
When Andy donates his toys and they see him leave in Toy Story 3.
When the imaginary friend sacrifices himself in Inside Out and is forgotten.

Fucking Pixar 

(that Up scene is probably an all-timer though)

[Zanza]

The girl in the red jacket in Schindler's List.

[Josquius]

Seymour is the correct answer.

[Barrister]

Opening scenes from Up.

When Miguel sings with his mom in Coco.
When Andy donates his toys and they see him leave in Toy Story 3.
When the imaginary friend sacrifices himself in Inside Out and is forgotten.

Fucking Pixar 

(that Up scene is probably an all-timer though)

Yup - Pixar knows how to be emotionally manipulative.

I feel like I was /thread with my answer though - nothing is as devastating as the scene from Up.

[The Larch]

My mother would say "Sophie's choice" for sure. She hasn't been able to watch another movie that even tangentially deals with the Holocaust since then.

[Grey Fox]

Any scenes that deal with the realization that adulthood is beginning and the endless dreams of the young are no longer possible for the characters.

[The Brain]

[Tonitrus]

[Admiral Yi]

Just rewatched the soap beatdown scene in Full Metal Jacket.  That scene is pretty intense.

[grumbler]

I thought that the Broken Arrow scene in We Were Soldiers... was pretty emotional, especially when they blended it into the actual photos Galloway took that day.

[celedhring]

Related, but myself I find it very difficult to feel emotion for stuff that happens onscreen - I'm just too aware a movie is a creation, it's not "real". I get intellectual enjoyment and entertainment (which I guess are emotions too), but the kind of empathic "emotion" for what the characters are experiencing, which is probably what we're talking about here, has always been difficult.
The exception is when it's something that directly speaks to my own experience or fears (that is why the opening of Up! is so damn effective for me).
It also works with real stories, or stories set around real events (like movies depicting the Holocaust).

How does that work for you?